Post-Doctoral Fellow

This postdoctoral position is to support the CLINNOVA project, a flagship precision medicine initiative across Luxembourg, France, Germany, and Switzerland. Clinnova focuses on immune-mediated diseases: inflammatory bowel disease (IBD), multiple sclerosis (MS), and rheumatoid diseases (RD). The project involves large prospective cohorts and the collection of multi-modal data, including clinical, imaging, and multi-omics (metagenomics, metabolomics, immune profiling) data. We are seeking a researcher to strengthen our efforts on metagenomics data analysis and its integration with other data modalities to identify biomarkers of disease progression and treatment response.

Key Accountabilities

• Lead the bioinformatic analysis of metagenomics data from human stool samples at BioAI unit
• Integrate metagenomic data with clinical, metabolomic, and immune profiling data using advanced techniques
• Together with our bioinformatician, develop and maintain bioinformatics workflows for reproducible, large-scale data processing
• Support the development of interpretable AI/ML models to stratify patients and predict treatment outcome
• Contribute to data curation and quality control across international partners
• Contribute to other multi-omics studies at LIH (e.g. MVD – Minimal Viable Dataset – initiative or/and MARKOPOLO project)
• Assess feasibility and contribure to developing disease maps potentially built for MVD and MARKOPOLO
• Publish results in peer-reviewed journals and present at international conferences

Key Skills, Experience and Qualifications

• PhD in Bioinformatics, Computational Biology, Microbiology, or related field
• Demonstrated expertise in metagenomics, especially in human microbiome data
• Proficiency in bioinformatics tools, scripting languages (R, Python), and HPC environments
• Strong knowledge of multi-omics data integration and statistical analysis
• Knowledge of gene pathway analysis and gene regulatory networks
• Familiarity with microbiome-related biomarkers, network analysis, and/or systems biology
• Strong track record of scientific publications and interdisciplinary collaboration
• Strong verbal and written communication skills for effective collaboration and dissemination of findings
• Understanding of ethical considerations, data privacy, and compliance in the context of bioinformatics research
  
  

Gender Equality

The LIH is an equal opportunities employer. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff. The LIH is attentive to gender representation among its leadership staff and aims to eliminate obstacles to the recruitment and promotion of female leaders and their career development.