SCIENTIFIC PUBLICATIONS
LIH researchers strive to generate meaningful and disease-relevant knowledge and results for national and European patients. Their findings are regularly published in prestigious international peer-reviewed journals, thereby extending the reach and visibility of the institute’s impact.
Scientific publications
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Personalized functional profiling using ex-vivo patient-derived spheroids points out the potential of an antiangiogenic treatment in a patient with a metastatic lung atypical carcinoid – 31/12/2022
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ORFhunteR – 01/05/2022
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Differences and Interactions in Placental Manganese and Iron Transfer across an In Vitro Model of Human Villous Trophoblasts – 18/03/2022
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Noncoding RNAs in age-related cardiovascular diseases – 16/03/2022
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Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies – 16/03/2022
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Is vitamin A an antioxidant? – 16/03/2022
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Wearable technology in orthopedic trauma surgery – An AO trauma survey and review of current and future applications – 15/03/2022
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Chimpanzee exposure to pollution revealed by human biomonitoring approaches – 15/03/2022
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The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD – 14/03/2022
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Trained through generations – 11/03/2022
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Consensus guidelines for the validation of qRT-PCR assays in clinical research by the CardioRNA consortium – 10/03/2022
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Carbonic Anhydrase IX – 09/03/2022
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A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise – 08/03/2022
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Surgical simulation training should become a mandatory part of orthopaedic education – 28/02/2022
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Comparison of Acetabular Labral Reconstruction With 7-mm Tibialis Anterior Allograft and 5-mm Iliotibial Band Autograft at Minimum 2-Year Follow-up – 28/02/2022
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Tolerable upper intake level for dietary sugars – 28/02/2022
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Safety of dried coffee husk (cascara) from Coffea arabica L. as a Novel food pursuant to Regulation (EU) 2015/2283 – 25/02/2022
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Additive Effect of Dopaminergic Medication on Gait Under Single and Dual-Tasking Is Greater Than of Deep Brain Stimulation in Advanced Parkinson Disease With Long-duration Deep Brain Stimulation – 25/02/2022
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Regulating Proteasome Activity – 23/02/2022
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Editorial – 23/02/2022
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Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing Ligand – 21/02/2022
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Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration – 18/02/2022
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Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020 – 15/02/2022
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PINK1 Protects against Staurosporine-Induced Apoptosis by Interacting with Beclin1 and Impairing Its Pro-Apoptotic Cleavage – 15/02/2022
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Measles – 12/02/2022
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Stress hormone signalling inhibits Th1 polarization in a CD4 T-cell-intrinsic manner via mTORC1 and the circadian gene PER1 – 10/02/2022
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Prevalence of hepatitis E virus antibodies in cattle in Burkina Faso associated with swine mixed farming – 09/02/2022
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Retrograde Procedural Memory in Parkinson’s Disease – 09/02/2022
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Editorial – 03/02/2022
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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress – 01/02/2022
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Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson’s disease – 29/01/2022
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Analysis of the Origin and Dissemination of HIV-1 Subtype C in Bulgaria – 27/01/2022
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COVID-19 – 27/01/2022
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Spatiotemporal and Ground-Reaction Force Characteristics as Risk Factors for Running-Related Injury – 20/01/2022
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Improving Diabetes-Related Biomedical Literature Exploration in the Clinical Decision-making Process via Interactive Classification and Topic Discovery – 18/01/2022
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Editorial – 17/01/2022
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Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection – 13/01/2022
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The role of serum 25 (OH) vitamin D level in the correlation between lipid profile, body mass index (BMI), and blood pressure – 13/01/2022
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Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease – 13/01/2022
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A Hot Topic – 12/01/2022
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Dairy Intake and Parkinson’s Disease – 08/01/2022
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Burden of non-communicable disease studies in Europe – 07/01/2022
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DYT6 mutated THAP1 is a cell type dependent regulator of the SP1 family – 07/01/2022
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Clinical and biological risk factors associated with inflammation in patients with type 2 diabetes mellitus – 06/01/2022
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Unexpectedly High Prevalence of Hepatitis C Virus Infection, Southern Laos – 01/01/2022
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Safety of hydrothermally treated kernels from edible Jatropha curcas L. (Chuta) as a novel food pursuant to Regulation (EU) 2015/2283 – 01/01/2022
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Guidance for establishing and applying tolerable upper intake levels for vitamins and essential minerals – 01/01/2022
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AllergoOncology – 01/01/2022
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Determinants of Self-Stigma in People with Parkinson’s Disease – 01/01/2022
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Prevalence and Cost of Care for Parkinson’s Disease in Luxembourg – 01/01/2022
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Lower impact forces but greater burden for the musculoskeletal system in running shoes with greater cushioning stiffness – 01/01/2022
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Das Knie im Spitzensport – 01/01/2022
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Allgemeinärzte raten nach einer Gesundheitskampagne nicht zu mehr körperlicher Aktivität – 01/01/2022
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A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia – 01/01/2022
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Brominated flame retardants, a cornelian dilemma – 01/01/2022
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DJ-1 depletion prevents immunoaging in T-cell compartments – 01/01/2022
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Safety of oil from Schizochytrium sp. (strain ATCC 20889) for use in infant and follow-on formula as a novel food pursuant to Regulation (EU) 2015/2283 – 01/01/2022
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Wearable gait analysis systems – 01/01/2022
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Ungewöhnliche Ursache für lumbale Beschwerden im Leistungssport – 01/01/2022
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Machine learning and conventional statistics – 01/01/2022
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Eine ausführliche Analyse des Side Hop Tests bei Patienten 9 Monate nach Rekonstruktion des vorderen Kreuzbandes – 01/01/2022
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Introgressive hybridisation between domestic pigs (Sus scrofa domesticus) and endemic Corsican wild boars (S. s. meridionalis) – 01/01/2022
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Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson’s Disease – 01/01/2022
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Gonadotropins as novel active partners in vascular diseases – 01/01/2022
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Impact of COVID-19 Pandemic on (Health) Care Situation of People with Parkinson’s Disease in Germany (Care4PD) – 31/12/2021
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Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors – 29/12/2021
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Patient-oriented perspective on chemokine receptor expression and function in glioma – 28/12/2021
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Association between Dietary Factors and Constipation in Adults Living in Luxembourg and Taking Part in the ORISCAV-LUX 2 Survey – 28/12/2021
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Safety of Eurycoma longifolia (Tongkat Ali) root extract as a novel food pursuant to Regulation (EU) 2015/2283 – 22/12/2021
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The european prevalence of resistance associated substitutions among direct acting antiviral failures – 22/12/2021
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Safety of Wolffia globosa powder as a Novel food pursuant to Regulation (EU) 2015/2283 – 22/12/2021
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Safety of tetrahydrocurcuminoids from turmeric (Curcuma longa L.) as a novel food pursuant to Regulation (EU) 2015/2283 – 22/12/2021
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Cancer cell heterogeneity and plasticity – 21/12/2021
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Leveraging non-coding RNAs to fight cardiovascular disease – 21/12/2021
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Multimorbidity in large Canadian urban centres: A multilevel analysis of pooled 2015–2018 cross-sectional cycles of the Canadian Community Health Survey – 20/12/2021
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Exercise-Based Injury Prevention in High-Level and Professional Athletes – 17/12/2021
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Critical Assessment of MetaProteome Investigation (CAMPI) – 15/12/2021
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Editorial – 15/12/2021
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Examining the double burden of malnutrition for preschool children and women of reproductive age in low-income and middle-income countries – 14/12/2021
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Associations Between Device-Measured Physical Activity and Glycemic Control and Variability Indices Under Free-Living Conditions – 14/12/2021
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Safety of iron hydroxide adipate tartrate as a novel food pursuant to Regulation (EU) 2015/2283 and as a source of iron in the context of Directive 2002/46/EC – 10/12/2021
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Intraoperative discrimination of native meningioma and dura mater by Raman spectroscopy – 08/12/2021
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Dietary intake of adult residents in luxembourg taking part in two cross-sectional studies—oriscav-lux (2007–2008) and oriscav-lux 2 (2016–2017) – 07/12/2021
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Clustering of obesity-related characteristics – 01/12/2021
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Analyses of blood donor samples from eight provinces in Lao PDR suggest considerable variation concerning HBV exposure and carriage – 01/12/2021
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An age-stratified serosurvey against purified Salmonella enterica serovar Typhi antigens in the Lao People´s Democratic Republic – 01/12/2021
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Novel Advances in Allergy Diagnosis and Treatment – 01/12/2021
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Estimated visceral adiposity is associated with risk of cardiometabolic conditions in a population based study – 01/12/2021
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Only limited correlations between patient-reported outcomes and objectively monitored physical activity 10-years after THA – 01/12/2021
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Methods to Generate Innovative Research Ideas and Improve Patient and Public Involvement in Modern Epidemiological Research – 01/12/2021
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Outcome of revised metal-on-metal hip arthroplasties – 30/11/2021
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The Th17 cell – IL22 axis depends on glutathione upon intestinal inflammation – 29/11/2021
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Tert promoter mutations increase sense and antisense transcription from the tert promoter – 26/11/2021
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Randomised crossover trial comparing algorithms and averaging times for automatic oxygen control in preterm infants – 24/11/2021
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Early-life adversity leaves its imprint on the oral microbiome for more than 20 years and is associated with long-term immune changes – 24/11/2021
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The antioxidant glutathione as a regulator of natural killer cell immunity – 21/11/2021
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DNA Repair and Innate Immune Response in Glioblastoma – PROJECT REPORT, November 2021 – 19/11/2021
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Unravelling data for rapid evidence-based response to COVID-19 – 18/11/2021
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Impact of small extracellular vesicles on anti-tumor immunity in chronic lymphocytic leukemia in vivo – 17/11/2021
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Special issue “microglia heterogeneity and its relevance for translational research” – 16/11/2021
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Impact of epithelial to mesenchymal transition on the regulation of anti-tumour immune response in breast cancer – 16/11/2021
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Effect of creatine and EDTA supplemented diets on European seabass (Dicentrarchus labrax) allergenicity, fish muscle quality and omics fingerprint – 16/11/2021
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Comparison of three galenic forms of lamivudine in young West African children living with Human Immunodeficiency Virus – 16/11/2021
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Safety of water lentil powder from Lemnaceae as a Novel Food pursuant to Regulation (EU) 2015/2283 – 15/11/2021
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Personalized drug screening for functional tumor profiling – 15/11/2021
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High nevirapine levels in breast milk and consequences in HIV-infected child when initiated on antiretroviral therapy – 15/11/2021
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(Eco)toxicological tests for assessing impacts of chemical stress to aquatic ecosystems – 15/11/2021
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Extension of use of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283 – 12/11/2021
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Impact of chromatin dynamics and dna repair on genomic stability and treatment resistance in pediatric high‐grade gliomas – 12/11/2021
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Relevance of Frequency-Domain Analyses to Relate Shoe Cushioning, Ground Impact Forces and Running Injury Risk – 11/11/2021
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IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation – 09/11/2021
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Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function – 09/11/2021
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Food-allergic patients: from phenotype to endotype for biomarker discovery – 09/11/2021
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Biomarkers for detection of lung cancer – 04/11/2021
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Signaling, function and modulation of CXCR3 variants – 03/11/2021
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Dietary modulation alters susceptibility to listeria monocytogenes and salmonella typhimurium with or without a gut microbiota – 02/11/2021
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Mondo-A Maintains Aggressiveness in Common Acute Lymphoblastic Leukemia (B-All) by Modulating the Metabolic Stress Response and can be Targeted by a Designer Drug – 01/11/2021
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Multiomic single nucleus RNA- and ATACSEQ profiling reveals regulators of glioma cell state diversity – 01/11/2021
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Detection of COVID-19 from voice, cough and breathing patterns – 01/11/2021
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Raman spectroscopy as a diagnostic tool in neuropathology – 01/11/2021
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The role of IDH1 R132H mutation in glioma an investigation by genome-editing in human induced pluripotent stem cells – 01/11/2021
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EntropyHub – 01/11/2021
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A DNA Damage Repair Signature in Pediatric High-Grade Gliomas: XRCC1 and PARP1, Key Biomarkers – 01/11/2021
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Inhibition of GBM invasion by the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonist Perampanel – 01/11/2021
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Investigating T cells in the context of Neuroimmunology: Molecular and cellular mechanisms during a stress response and a patient-based study in Parkinson’s disease – 01/11/2021
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European Health Interview Survey (EHIS): Obésité, Nutrition et Activité physique – 3 ème vague – 2019 (Fact sheet) – 01/11/2021
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Relevance of N6-methyladenosine regulators for transcriptome – 01/11/2021
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New section on carbohydrate epitopes in the WHO/IUIS allergen nomenclature website – 01/11/2021
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Vicilin IgE-cross-reactivity is responsible for in vitro allergenicity to cowpea in patients with legume allergy – 01/11/2021
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Validation of a sensor-based gait analysis system with a gold-standard motion capture system in patients with parkinson’s disease – 01/11/2021
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Raman spectroscopy as a tool in neurosurgery – 01/11/2021
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Allergy burden in luxembourg: A population-based, cross-sectional health survey paralleled by component-resolved-IgE-diagnosis – 01/11/2021
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Exploring the contribution of the mitochondrial disulfide relay system to Parkinson’s disease – 01/11/2021
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Whey-and soy protein isolates added to a carrot-tomato juice alter carotenoid bioavailability in healthy adults – 31/10/2021
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Intérêt d’une approche géostatistique pour analyser les disparités géographiques de la couverture vaccinale contre les papillomavirus humains en France – 30/10/2021
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Digital technology and disease surveillance in the COVID-19 pandemic – 29/10/2021
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An adaptive network model of the role of the gut-brain axis in parkinson’s disease – 29/10/2021
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Safety of the extension of use of galacto-oligosaccharides as a Novel food pursuant to Regulation (EU) 2015/2283 – 27/10/2021
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Transcriptional cooperation of PBX1 and PAX6 in adult neural progenitor cells – 25/10/2021
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Advanced analytical methods to assess physical activity behavior using accelerometer time series – 25/10/2021
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The Moderating Role of Resilience in the Personality-Mental Health Relationship During the COVID-19 Pandemic – 21/10/2021
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Safety of mung bean protein as a novel food pursuant to Regulation (EU) 2015/2283 – 20/10/2021
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Organic foods and contribution to the protection of body cells and molecules (lipids and DNA) from oxidative damage: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 – 20/10/2021
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The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 – 19/10/2021
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Current landscape and future perspectives in preclinical MR and PET imaging of brain metastasis – 14/10/2021
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Peripheral blood RNA biomarkers for cardiovascular disease from bench to bedside – 14/10/2021
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Waning of maternal antibodies against measles suggests a large window of susceptibility in infants in lao people’s Democratic republic – 13/10/2021
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Parkinson’s Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment – 12/10/2021
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In silico approach for validating and unveiling new applications for prognostic biomarkers of endometrial cancer – 09/10/2021
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Gastric lipase can significantly increase lipolysis and carotenoid bioaccessibility from plant food matrices in the harmonized INFOGEST static in vitro digestion model – 04/10/2021
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Differentiation of primary CNS lymphoma and glioblastoma using Raman spectroscopy and machine learning algorithms – 04/10/2021
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DECONbench – 02/10/2021
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Maraviroc prevents hcc development by suppressing macrophages and the liver progenitor cell response in a murine chronic liver disease model – 01/10/2021
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Management of anaphylaxis due to COVID-19 vaccines in the elderly – 01/10/2021
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Global, regional, and national burden of stroke and its risk factors, 1990-2019 – 01/10/2021
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Unraveling the concepts of distress, burnout, and depression in type 1 diabetes – 01/10/2021
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Does prevention pay off? – 01/10/2021
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Isomaltulose and normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 – 01/10/2021
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Rubella epidemiology in the Central African Republic, 2015-2016 and molecular characterization of virus strains from 2008-2016 – 01/10/2021
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Declining incidence of HIV multidrug resistance in Europe – 01/10/2021
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Non-coding RNAs and stem cells – 01/10/2021
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Systems and Longitudinal Analysis Reveals Early-Stage and Highly Coordinated Immune Responses in Mild COVID-19 Patients – 30/09/2021
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Injuries in the European Union 2009-2018 – 30/09/2021
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Synthetic retinoids as potential therapeutics in prostate cancer—An update of the last decade of research – 29/09/2021
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A new brain organoid model to study Parkinson’s Disease – 28/09/2021
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Proficiency testing program celebrates its 10th anniversary – 28/09/2021
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A dangeROS liaison: the metabolism-dependent regulation of B lymphocytes – 28/09/2021
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Population birth data and pandemic readiness in Europe – 27/09/2021
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XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase – 27/09/2021
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Integrative genomics analysis of nasal intestinal-type adenocarcinomas demonstrates the major role of CACNA1C and paves the way for a simple diagnostic tool in male woodworkers – 25/09/2021
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Computationally designed GPCR quaternary structures bias signaling pathway activation – 23/09/2021
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TGF-β promotes microtube formation in glioblastoma through thrombospondin 1 – 20/09/2021
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Deprivation of dietary fiber in specific-pathogen-free mice promotes susceptibility to the intestinal mucosal pathogen Citrobacter rodentium – 18/09/2021
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An antigen microarray protocol for COVID-19 serological analysis – 17/09/2021
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Commentary – 16/09/2021
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Multi-omics analysis to decipher the molecular link between chronic exposure to pollution and human skin dysfunction – 15/09/2021
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IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria – 13/09/2021
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Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019 – 11/09/2021
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Inhibition of GBM invasion by the A-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid (AMPA) Glutamate receptor antagonist Perampanel – 09/09/2021
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Tumour Immune Evasion is Promoted by Actin Cytoskeleton-Driven Polarization of Inhibitory Signals to the Immunological Synapse – 09/09/2021
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The tumor microenvironment-dependent transcription factors ahr and hif-1α are dispensable for leukemogenesis in the eµ-tcl1 mouse model of chronic lymphocytic leukemia – 08/09/2021
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“Suffocating” tumors by blocking adaptation to hypoxia – 07/09/2021
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Epigenetic regulation via PRMT7 controls monocyte migration and COPD pathogenesis – 05/09/2021
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BMI in the Associations of Plant-Based Diets with Type 2 Diabetes and Hypertension Risks in Women – 04/09/2021
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Atopic Dermatitis Patients with Pet Dander Sensitization Mount IgE and T cell Responses to Mammalian Cystatins Including the Human Self-Protein – 03/09/2021
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Deep immune profiling reveals early-stage and highly coordinated immune responses in mild COVID-19 patients – 02/09/2021
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Phenotypic heterogeneity and plasticity as resistance mechanisms in glioblastoma – 01/09/2021
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The gut commensal Bacteroides vulgatus mpk reduces Candida albicans pathogenicity towards epithelial cells – 01/09/2021
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Effectiveness of integrase strand transfer inhibitor-based regimens in HIV-infected treatment-naive individuals – 01/09/2021
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Non-invasive, neurotoxic surgery reduces seizures in a rat model of temporal lobe epilepsy – 01/09/2021
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Novel thioridazine derivates: antiproliferative and apoptosis-inducing activity on glioblastoma cells in vitro – 01/09/2021
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The circadian clock remains intact, but with dampened hormonal output in heart failure – 01/09/2021
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Metastatic potential of systemic glioblastoma stem cell lines in vivo – 01/09/2021
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Troubles musculosquelettiques au cours du diabète de type 1 – 01/09/2021
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Loss of williams syndrome transcription factor (WSTF) leads to improved temozolomide sensitivity in human glioblastoma cells irrespective of MGMT expression – 01/09/2021
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Allergic airway inflammation impacts tumor take and delays experimental glioblastoma progression – 01/09/2021
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La traduction et la synthèse des positions de consensus du CIO – 01/09/2021
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Visceral Fat Calculator – 01/09/2021
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La traduction et la synthèse des positions de consensus du CIO – 01/09/2021
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The conundrum of low covid-19 mortality burden in sub-saharan africa – 01/09/2021