Infection and Immunotherapy Research Group
The goal of the Infection and Immunotherapy Research (IIR) is to develop new immunotherapies against infectious diseases and cancer. They aim to provide a new translational understanding on HIV cure, bacterial infections and of cancer immunology. The group is also involved in clinical research working towards the elimination of HIV and Hepatitis in Luxembourg.
Aims and objectives
We focus on the development of immunotherapeutic complexes and NK cell engagers boosting innate immunity against viruses, bacteria and cancer cells for further elimination by the immune system. Our research encompasses protein engineering, virology, bacteriology, immunoassays and preclinical studies for the design of targeted therapeutic approaches.
HIV and viral hepatitis elimination
Our group support the monitoring of HIV and Hepatitis elimination in Luxembourg, as part of international research and surveillance networks, through outreach projects and clinical studies from the national HIV and Hepatitis programmes.
Seguin-Devaux
Projects & clinical trials
Featured team members
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Carole
Devaux Group Leader and Deputy Head Quality & Safety -
Gilles
Iserentant Research Engineer -
Aubin
Pitiot Postdoctoral Fellow -
Camille
Rolin PhD Student -
Jean-Yves
Servais Research Engineer
Scientific publications
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Bridging the gap with multispecific immune cell engagers in cancer and infectious diseases – 01/01/2024
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Adoptive T Regulatory Cell Therapy Takes an Important Step – 01/06/2024
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Solving the antibacterial resistance in Europe – 17/02/2024
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Two hits are better than one – 30/04/2024
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Direct-acting antiviral therapies for hepatitis C infection – 01/04/2024
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Flow cytometry conjugate formation assay between natural killer cells and their target cells – 11/03/2024
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HIV and people who inject drugs – 01/01/2024
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Prevalence of chronic HCV infection in EU/EEA countries in 2019 using multiparameter evidence synthesis – 01/01/2024
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The Role of Late Presenters in HIV-1 Transmission Clusters in Europe – 13/12/2023
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Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure – 07/11/2023
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