Abteilung für Krebsforschung (DOCR)
Unsere Vision ist es, das Leben der Patienten zu verbessern, indem wir den Kampf gegen Krebs vorantreiben. Auf der Grundlage solider wissenschaftlicher Ergebnisse konzentrieren wir uns auf vorrangige Forschungsbereiche und bieten Forschungsexpertise zu den häufigsten und/oder bösartigsten Krebsarten, die in Luxemburg eine Gesundheitsbelastung darstellen. Die Abteilung stellt auch eine hochmoderne Ausbildungsstätte für die nächste Generation von Krebsforschern dar und fungiert als Referenzpunkt für die Krebsforschung in Luxemburg.
Aufgaben
Die Hauptaufgabe des Department of Cancer Research besteht darin, die Optionen für die Behandlung von Krebs zu erweitern und zu verbessern sowie die Krebslast in der luxemburgischen Bevölkerung und darüber hinaus zu verringern. Wir tun dies durch exzellente Forschung in Prioritätsbereichen, die von der Grundlagen- über die translationale bis zur klinischen Forschung reichen, um Programme für personalisierte Medizin zu fördern. Der Schwerpunkt unserer Aktivitäten liegt auf schwer zu behandelnden Krebsarten, und unsere Teams verfügen jeweils über Spezialkompetenzen in Krebsimmunologie, der Mikroumgebung von Tumoren, Tumorstoffwechsel und Neuroonkologie. Wir erforschen die zellulären und molekularen Mechanismen der Tumorprogression mithilfe einer breiten Palette modernster Technologien, u. a. multimodalen Omik-Technologien (Genomik, Metabolomik…), erweiterten Analysen zur Immunprofilierung sowie Ex-vivo- und In-vivo-Bildgebungsmodalitäten, für die wir Patientendaten und innovative patientenabgeleitete Modelle für die Krebsforschung nutzen.
LEITUNG DES DEPARTMENT
Meiser
- DNA-Reparatur und Chemoresistenz
- Gruppe Krebs-Stoffwechsel
- In-vivo-Bildgebung
- Luxemburger Zentrum für Neuropathologie
- Multi-omics Data Science Forschung
- NORLUX-Labor für Neuro-Onkologie
- Neuro-Immunologie Gruppe
- Translationale Krebsimmunogenomik
- Translationale Radiomik
- Tumorimmuntherapie und Mikroumgebung
- Wechselwirkungen von Tumorstroma
- Zytoskelett und Krebsausbreitung
Projekte und klinische Versuche
Ausgewählte Teammitglieder
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Rafael
Barros Laboratory Assistant -
Elisabetta
Bartolini PhD Student -
Michaela
Bauer Postdoctoral Fellow -
Amandine
Bernard Laboratory Technician -
Coralie
Borne Postdoctoral Fellow -
Selma
Boudissa Research Engineer -
Eleonora
Campus PhD Student -
Maryna
Chepeleva PhD Student -
Valentina
Delli Zotti Visiting Researcher -
Chloé
Duculty PhD Student -
Iria
Fernandez Botana Postdoctoral Fellow -
Liza
Filali Postdoctoral Fellow -
Ruize
Gao Postdoctoral Fellow -
Melike
Gezen Postdoctoral Fellow -
Ozgu
Gumustekin PhD Student -
Céline
Hoffmann Scientist -
Wanxin
Huang PhD Student -
Bassam
Janji Group Leader -
Maxmilan
Jeyakumar Postdoctoral Fellow -
Georgia
Kanli Research Engineer -
Olivier
Keunen Group Leader -
Vanessa
Klapp PhD Student -
Akinchan
Kumar Postdoctoral Fellow -
Anne
Largeot Scientist -
Frida
Lind-Holm PhD Student -
Beatrice
Melin Visiting Researcher -
Takouhie
Mgrditchian Postdoctoral Fellow -
Alessandro
Michelucci Group Leader -
Flora
Moreau Laboratory Technician -
Etienne
Moussay Group Leader -
Petr
Nazarov Group Leader -
Bakhtiyor
Nosirov Postdoctoral Fellow -
Jérôme
Paggetti Group Leader -
Valérie
Palissot Scientist -
Diogo
Pereira Fernandes PhD Student -
Daniele
Perlo Postdoctoral Fellow -
Michaela
Pešová Postdoctoral Fellow -
Sandrine
Pierson Research Engineer -
Aurélie
Poli Scientist -
Margaux
Poussard Postdoctoral Fellow -
Teresa
Ramos Postdoctoral Fellow -
Lucie
Rospape PhD Student -
Francesca Maria
STEFANIZZI Postdoctoral Fellow -
Andrea
Scafidi PhD Student -
Danial
Tabbakh PhD Student -
Clément
Thomas Group Leader -
Reka
Toth Scientist -
Kris
Van Moer Research Engineer -
Alice
Verdier PhD Student -
Elodie
Viry Postdoctoral Fellow -
Guillaume
Vogin Clinician Scientist
Wissenschaftliche Veröffentlichungen
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Is the tumor cell side of the immunological synapse a polarized secretory domain? – 24/09/2024
Clément Thomas und 6 weitere autoren -
A comprehensive guide to study the immunological synapse using imaging flow cytometry – 03/04/2024
Céline Hoffmann und 3 weitere autoren -
Actin remodeling in autophagy-mediated tumor immune escape, mechanistic aspects – 08/12/2023
Andrea Michela Biolato -
CSPG4 CAR-redirected Cytokine Induced Killer lymphocytes (CIK) as effective cellular immunotherapy for HLA class I defective melanoma – 22/11/2023
Dario Sangiolo und 26 weitere autoren -
Actin cytoskeleton remodeling at the cancer cell side of the immunological synapse – 21/09/2023
Clément Thomas und 4 weitere autoren -
Correlative light and electron microscopy to explore the lytic immunological synapse between natural killer cells and cancer cells – 05/06/2023
Felix K Borgmann und 4 weitere autoren -
The Immunological Synapse Part B – 11/07/2023
Clément Thomas und 1 weiterer autor -
Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus – 15/05/2023
Clément Thomas und 10 weitere autoren -
Measuring CTL Lytic Granule Secretion and Target Cell Membrane Repair by Fluorescent Lipophilic Dye Uptake at the Lytic Synapse – 28/04/2023
Salvatore Valitutti und 3 weitere autoren -
An integrated workflow for phosphopeptide identification in natural killer cells (NK-92MI) and their targets (MDA-MB-231) during immunological synapse formation – 09/02/2023
Gunnar Dittmar und 3 weitere autoren -
The Immunological Synapse Part A – 11/01/2023
Clément Thomas und 1 weiterer autor -
Ultrarapid lytic granule release from CTLs activates Ca2+-dependent synaptic resistance pathways in melanoma cells – 01/02/2022
Salvatore Valitutti und 13 weitere autoren -
Tumour Immune Evasion is Promoted by Actin Cytoskeleton-Driven Polarization of Inhibitory Signals to the Immunological Synapse – 09/09/2021
Hannah Wurzer -
How natural killer cells avoid self-destruction when killing their targets – 01/08/2021
Clément Thomas und 2 weitere autoren -
Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling – 24/05/2021
Clément Thomas und 11 weitere autoren -
Actin Cytoskeleton in Cancer Progression and Metastasis – Part C – 04/05/2021
Clément Thomas und 1 weiterer autor -
Illuminating the signaling enigma of Carvedilol – 01/03/2021
Tobias Benkel und 21 weitere autoren -
The multiple roles of actin-binding proteins at invadopodia – 01/01/2021
Clément Thomas und 4 weitere autoren -
Higher Incidence of B Cell Malignancies in Primary Immunodeficiencies – 09/11/2020
Clément Thomas und 4 weitere autoren -
Actin Cytoskeleton in Cancer Progression and Metastasis – Part B – 12/10/2020
Clément Thomas und 1 weiterer autor -
Escape of tumor cells from the NK cell cytotoxic activity – 01/10/2020
Massimo Vitale und 3 weitere autoren -
Actin Cytoskeleton in Cancer Progression and Metastasis – Part A – 25/08/2020
Clément Thomas und 1 weiterer autor -
The role of heparan sulfate maturation in cancer – 01/05/2020
Sandrine Gulberti und 2 weitere autoren -
Actin remodeling and vesicular trafficking at the tumor cell side of the immunological synapse direct evasion from cytotoxic lymphocytes – 01/01/2020
Andrea Michela Biolato und 6 weitere autoren -
Actin cytoskeleton straddling the immunological synapse between cytotoxic lymphocytes and cancer cells – 16/05/2019
Clément Thomas und 3 weitere autoren -
Do tumor cells escape from natural killer cell cytotoxicity by mimicking dendritic cells? – 29/03/2019
Clément Thomas und 3 weitere autoren -
Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2 – 01/12/2018
Clément Thomas und 9 weitere autoren -
Actin cytoskeleton remodeling drives breast cancer cell escape from natural killer-mediated cytotoxicity – 01/10/2018
Clément Thomas und 13 weitere autoren -
Role of the actin cytoskeleton in breast cancer cell resistance to natural killer cells – 06/07/2018
Antoun Al Absi -
Reactivation of mutant-EGFR degradation through clathrin inhibition overcomes resistance to EGFR tyrosine kinase inhibitors – 15/06/2018
Ludovic Ménard und 3 weitere autoren -
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT – 03/04/2018
Bassam Janji und 10 weitere autoren -
Driving cytotoxic natural killer cells into melanoma – 01/01/2018
Bassam Janji und 8 weitere autoren -
Subcellular localization and function of 2LIM proteins in plants and humans – 01/12/2017
Clément Thomas und 2 weitere autoren -
Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner – 31/10/2017
Bassam Janji und 15 weitere autoren -
The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer – 22/09/2016
Sylvie Fournel-Gigleux und 13 weitere autoren -
Digital skills for health professionals – 01/06/2016
F. Dalati und 10 weitere autoren -
TWISTED DWARF1 Mediates the Action of Auxin Transport Inhibitors on Actin Cytoskeleton Dynamics – 01/04/2016
Markus Geisler und 24 weitere autoren -
CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis – 22/03/2016
Clément Thomas und 8 weitere autoren -
The multifaceted role of autophagy in tumor evasion from immune surveillance – 01/01/2016
Bassam Janji und 12 weitere autoren -
The pH sensibility of actin-bundling LIM proteins is governed by the acidic properties of their C-terminal domain – 12/08/2015
Clément Thomas und 8 weitere autoren -
HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors – 25/06/2015
David G. Fernig und 4 weitere autoren -
Hypoxia: A key feature of the tumor microenvironment triggers several mechanisms of evasion from natural killer and cytotoxic T lymphocytes surveillance – 20/11/2014
Bassam Janji und 9 weitere autoren -
A dynamic interplay between membranes and the cytoskeleton critical for cell development and signaling – 16/07/2014
Clément Thomas und 1 weiterer autor -
Correction to Live cell imaging reveals actin-cytoskeleton-induced self-association of the actin-bundling protein WLIM1 [J. Cell Sci. 127, 583-598] – 01/03/2014
Céline Hoffmann und 8 weitere autoren -
Involvement of substance P/neurokinin-1 receptor in the analgesic and anticancer activities of minimally toxic fraction from the traditional Chinese medicine Liu-Shen-Wan in vitro – 01/03/2014
Xiao Jun Li und 4 weitere autoren -
Live cell imaging reveals actin-cytoskeleton-induced self-association of the actin-bundling protein WLIM1 – 01/02/2014
Clément Thomas und 8 weitere autoren -
Human muscle LIM protein dimerizes along the actin cytoskeleton and cross-links actin filaments – 01/01/2014
Clément Thomas und 8 weitere autoren -
A LIM domain protein from tobacco involved in actin-bundling and histone gene transcription – 01/03/2013
Danièle Moes und 11 weitere autoren -
Proteomic profiling of rapid non-genomic and concomitant genomic effects of acute restraint stress on rat thymocytes – 03/04/2012
Claude Muller und 5 weitere autoren -
Arabidopsis actin-depolymerizing factors (ADFs) 1 and 9 display antagonist activities – 23/06/2011
Clément Thomas und 8 weitere autoren -
Arabidopsis LIM proteins – 01/09/2010
Jessica Papuga und 7 weitere autoren -
Mouse natural killer (NK) cells express the nerve growth factor receptor TrkA, which is dynamically regulated – 01/01/2010
Jacques Zimmer und 5 weitere autoren -
Actin bundling in plants – 01/11/2009
Clément Thomas und 6 weitere autoren -
Actin bundling via LIM domains – 01/05/2008
Clément Thomas und 6 weitere autoren -
The LIM domains of WLIM1 define a new class of actin bundling modules – 16/11/2007
Clément Thomas und 8 weitere autoren -
Protocol for immunofluorescence staining and large-scale analysis to quantify microglial cell morphology at single-cell resolution in mice – 04/12/2024
Alessandro Michelucci und 3 weitere autoren -
Multiomics approaches disclose very-early molecular and cellular switches during insect-venom allergen-specific immunotherapy – 26/11/2024
Markus Ollert und 41 weitere autoren -
Adenoviral delivery of the CIITA transgene induces T-cell-mediated killing in glioblastoma organoids – 13/11/2024
Simone P. Niclou und 13 weitere autoren -
Metformin impacts the differentiation of mouse bone marrow cells into macrophages affecting tumour immunity – 30/09/2024
Alessandro Michelucci und 15 weitere autoren -
Granulocytes and mast cells in AllergoOncology—Bridging allergy to cancer – 22/07/2024
Mariona Pascal und 18 weitere autoren -
PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation – 16/07/2024
Alessandro Michelucci und 20 weitere autoren -
AllergoOncology – 01/01/2024
Aurélie Poli und 29 weitere autoren -
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts – 02/04/2024
Anna Golebiewska und 24 weitere autoren -
Targeting the ACOD1-itaconate axis stabilizes atherosclerotic plaques – 01/04/2024
Menno PJ de Winther und 20 weitere autoren -
Multiomics approaches disclose very-early molecular and cellular switches during insect-venom allergen-specific immunotherapy – 22/02/2024
Feng Q Hefeng und 38 weitere autoren -
PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation – 09/02/2024
Alessandro Michelucci und 17 weitere autoren -
Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts – 12/12/2023
Anna Golebiewska und 21 weitere autoren -
SUSD2-IL-2 receptor interaction hinders antitumoral CD8+ T-cell activity – 01/01/2023
Ilaria Salvato und 2 weitere autoren -
A SPECT-based method for dynamic imaging of the glymphatic system in rats – 21/02/2023
Maiken Nedergaard und 12 weitere autoren -
PARK7/DJ-1 in microglia – 18/04/2023
Alessandro Michelucci und 3 weitere autoren -
Transcriptional and Chromatin Accessibility Profiling of Neural Stem Cells Differentiating into Astrocytes Reveal Dynamic Signatures Affected under Inflammatory Conditions – 21/03/2023
Alessandro Michelucci und 8 weitere autoren -
Allergic airway inflammation delays glioblastoma progression and reinvigorates systemic and local immunity in mice – 01/01/2022
Aurélie Poli und 16 weitere autoren -
Correction – 29/11/2022
Aaqib Sohail und 20 weitere autoren -
SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline – 21/10/2022
Maiken Nedergaard und 9 weitere autoren -
Adenovirus-mediated delivery of the MHC-II Transactivator CIITA gene induces tumor cell killing in immunocompetent glioblastoma organoids – 05/09/2022
Ilaria Salvato und 9 weitere autoren -
Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts – 05/09/2022
Yahaya Abubakar Yabo und 8 weitere autoren -
Modeling immunocompetent tumor microenvironment in glioblastoma patient-derived orthotopic xenografts – 05/09/2022
Pilar Maria Moreno Sanchez und 8 weitere autoren -
AllergoOncology – 01/01/2022
Sophia N. Karagiannis und 30 weitere autoren -
Elucidating tumour-associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency – 01/01/2022
Alessandro Michelucci und 13 weitere autoren -
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism – 01/05/2022
Frank Pessler und 20 weitere autoren -
Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson’s disease – 29/01/2022
Manuel Buttini und 24 weitere autoren -
Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection – 13/01/2022
Frank Pessler und 20 weitere autoren -
Special issue “microglia heterogeneity and its relevance for translational research” – 16/11/2021
Alessandro Michelucci und 2 weitere autoren -
IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation – 09/11/2021
Gerhard Krönke und 25 weitere autoren -
Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha-6 chain as a novel regulator of striatal axonal branching in mice – 01/01/2021
Manuel Buttini und 17 weitere autoren -
Allergic airway inflammation impacts tumor take and delays experimental glioblastoma progression – 01/09/2021
Aurélie Poli und 13 weitere autoren - Tumour-associated microglia/macrophage (TAM) heterogeneity in Glioblastoma – 22/06/2021
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Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors – 18/06/2021
Anaïs Oudin und 16 weitere autoren -
FAM13A regulates KLRG1 expression and interferon gamma production of natural killer cells – 18/05/2021
Ni Zeng und 14 weitere autoren -
Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus – 12/04/2021
Danielle PerezBercoff und 13 weitere autoren -
NF-kappa B and TNF Affect the Astrocytic Differentiation from Neural Stem Cells – 08/04/2021
Cindy Birck und 5 weitere autoren -
Microglia in Health and Disease – 31/03/2021
Alessandro Michelucci und 3 weitere autoren -
Single-cell transcriptomics and In situ morphological analyses reveal microglia heterogeneity across the nigrostriatal pathway – 29/03/2021
Alessandro Michelucci und 8 weitere autoren -
CpG Adjuvant in Allergen-Specific Immunotherapy – 23/02/2021
Markus Ollert und 3 weitere autoren -
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology – 01/12/2020
Simone Niclou und 40 weitere autoren -
Interrogating intratumoral transcriptomic heterogeneity and plasticity as resistance mechanisms in glioblastoma – 01/11/2020
Yahaya Abubakar Yabo und 8 weitere autoren -
Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging – 23/09/2020
Lasse Sinkkonen und 16 weitere autoren -
Revealing and harnessing tumour-associated microglia/macrophage heterogeneity in glioblastoma – 01/02/2020
Alessandro Michelucci und 1 weiterer autor -
BCL2L15 (BCL2-like 15) – 01/01/2020
Pinelopi I. Artemaki und 2 weitere autoren -
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment – 01/12/2019
Simone Niclou und 21 weitere autoren -
Allergooncology: Delayed glioblastoma progression in a mouse model of allergic airway inflammation – 01/08/2019
Aurélie Poli und 13 weitere autoren -
Region-specific microglial heterogeneity and its potential relevance for Parkinson’s disease – 01/07/2019
Oihane Uriarte Huarte und 8 weitere autoren -
Transcriptional and epigenetic mechanisms underlying astrocyte identity – 01/03/2019
Alessandro Michelucci und 4 weitere autoren -
Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures – 01/11/2018
Alessandro Michelucci und 11 weitere autoren -
Microglia in health and disease: A unique immune cell population – 01/09/2018
Alessandro Michelucci und 2 weitere autoren -
Single-cell transcriptomic analysis of microglia/macrophages in glioblastoma – 01/09/2018
Alessandro Michelucci und 6 weitere autoren -
Microglia in health and disease – 15/08/2018
Alessandro Michelucci und 2 weitere autoren -
Delayed glioblastoma progression by repeated nasal instillations of house dust mite extract in a mouse model – 01/08/2018
Aurélie Poli und 11 weitere autoren -
Human leukocyte antigen class I deficiencies – 01/06/2017
Jacques Zimmer und 2 weitere autoren -
Human CD56bright NK cells – 01/04/2016
Jacques Zimmer und 6 weitere autoren -
Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma – 30/09/2014
Cecilie Brekke Rygh und 11 weitere autoren -
Combining NK cells and mAb9.2.27 to combat NG2-dependent and anti-inflammatory signals in glioblastoma – 01/01/2014
Martha Chekenya Enger und 5 weitere autoren -
TAP deficiency is also a cause of bronchiectasis – 01/05/2013
Jacques Zimmer und 4 weitere autoren -
Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level – 01/01/2013
Martha Chekenya Enger und 7 weitere autoren -
Mouse Lung and Spleen Natural Killer Cells Have Phenotypic and Functional Differences, in Part Influenced by Macrophages – 05/12/2012
Tatiana Michel und 7 weitere autoren -
Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma – 01/10/2011
Martha Chekenya Enger und 21 weitere autoren -
Increased Th2 cytokine secretion, eosinophilic airway inflammation, and airway hyperresponsiveness in neurturin-deficient mice – 01/06/2011
Tatiana Michel und 7 weitere autoren -
Novel method for isolating untouched rat natural killer cells with higher purity compared with positive selection and fluorescence-activated cell sorting – 01/11/2010
Aurélie Poli und 6 weitere autoren -
NK cells and allergy – 01/01/2010
Tatiana Michel und 4 weitere autoren -
CD56bright natural killer (NK) cells – 01/04/2009
Jacques Zimmer und 5 weitere autoren -
A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions – 01/09/2008
Simone Niclou und 10 weitere autoren -
Control of NK cell functions by CD4+CD25+ regulatory T cells – 01/01/2007
Jacques Zimmer und 6 weitere autoren -
Reduced cytokine-mediated up-regulation of HLA-DR in TAP-deficient fibroblasts – 15/11/2006
Jacques Zimmer und 5 weitere autoren -
Quantitative pre-clinical imaging of hypoxia and vascularity using MRI and PET – 01/01/2024
Georgia Kanli und 9 weitere autoren -
Atypical chemokine receptor 2 expression is directly regulated by hypoxia inducible factor-1 alpha in cancer cells under hypoxia – 04/11/2024
Bassam Janji und 4 weitere autoren -
Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy – 01/01/2024
Bassam Janji und 22 weitere autoren -
Local relapse patterns after preoperative radiotherapy of limb and trunk wall soft tissue sarcomas – 26/07/2024
Guillaume Vogin und 17 weitere autoren -
Identification of the role of HIF-1α-dependent hypoxia in the regulation of ACKR2 (Atypical Chemokine Receptor 2) expression in cancer – 26/06/2024
Alice Benoit -
Improving STING agonist-based cancer therapy by inhibiting the autophagy-related protein VPS34 – 11/06/2024
Bassam Janji und 2 weitere autoren -
Hypoxia as a potential inducer of immune tolerance, tumor plasticity and a driver of tumor mutational burden – 28/11/2023
Salem Chouaib und 12 weitere autoren -
CyPep-1 reprograms the tumor microenvironment and enhances the efficacy of immune checkpoint inhibitors – 01/10/2023
Bassam Janji und 7 weitere autoren -
Lighting Up the Fire in the Microenvironment of Cold Tumors – 05/07/2023
Bassam Janji und 4 weitere autoren -
Nanoluciferase-based complementation assays to monitor activation, modulation and signaling of receptor tyrosine kinases (RTKs) – 24/12/2022
Andy Chevigne und 7 weitere autoren -
Prevention of acute GVHD disease using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T-cells in vivo – 23/12/2022
Teresa Ramos und 20 weitere autoren -
Dual blockage of both PD-L1 and CD47 enhances the therapeutic effect of oxaliplatin and FOLFOX in CT-26 mice tumor model – 11/02/2023
Seyed Amir Jalali und 8 weitere autoren -
Basic Concepts of Radiation Biology – 01/01/2023
Ans Baeyens und 30 weitere autoren -
Clinical Radiobiology for Radiation Oncology – 01/01/2023
Peter Sminia und 26 weitere autoren -
Individual Radiation Sensitivity and Biomarkers – 01/01/2023
Elizabeth A. Ainsbury und 19 weitere autoren -
Radiobiology of Accidental, Public, and Occupational Exposures – 01/01/2023
Ruth Wilkins und 17 weitere autoren -
Space Radiobiology – 01/01/2023
Yehoshua Socol und 24 weitere autoren -
A role for EMT in CD73 regulation in breast cancer – 30/11/2022
Bassam Janji und 2 weitere autoren -
The β-carboline Harmine improves the therapeutic benefit of anti-PD1 in melanoma by increasing the MHC-I-dependent antigen presentation – 15/11/2022
Bassam Janji und 8 weitere autoren -
Hypoxia features as potential indicators in prognosis, immunotherapy and drug screening in hepatocellular carcinoma patients – 12/10/2022
Ruize Gao -
Improving neuroblastoma therapy by targeting intratumoral hypoxia and immune checkpoint PD-L1 – 23/09/2022
Delphine Sauvage -
SNAI1-dependent upregulation of CD73 increases extracellular adenosine release to mediate immune suppression in TNBC – 09/09/2022
Bassam Janji und 13 weitere autoren -
The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model – 06/09/2022
Bassam Janji und 7 weitere autoren -
Combining ablative radiotherapy and anti CD47 monoclonal antibody improves infiltration of immune cells in tumor microenvironments – 26/08/2022
Seyed Amir Jalali und 10 weitere autoren -
Radiation dose and schedule influence the abscopal effect in a bilateral murine CT26 tumor model – 10/04/2022
Seyed Amir Jalali und 8 weitere autoren -
The Promise of Targeting Hypoxia to Improve Cancer Immunotherapy – 20/06/2022
Bassam Janji und 1 weiterer autor -
VPS34 inhibitor SB02024 activates cGAS-STING signaling and sensitizes tumors to STING agonist – 15/06/2022
Yasmin Yu und 11 weitere autoren -
The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B – 01/06/2022
Andy Chevigne und 10 weitere autoren -
CMTM6 and CMTM7 – 01/01/2022
Bassam Janji und 4 weitere autoren -
Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis – 16/05/2022
Johannes Meiser und 18 weitere autoren -
Editor’s Note – 15/04/2022
Yosra Messai und 21 weitere autoren -
Carbonic Anhydrase IX – 09/03/2022
Najla Santos Pacheco de Campos und 7 weitere autoren -
Nanoluciferase-based methods to monitor activation, modulation and trafficking of atypical chemokine receptors – 18/04/2022
Martyna Szpakowska und 9 weitere autoren -
Impact of epithelial to mesenchymal transition on the regulation of anti-tumour immune response in breast cancer – 16/11/2021
Malina Xiao -
Maraviroc prevents hcc development by suppressing macrophages and the liver progenitor cell response in a murine chronic liver disease model – 01/10/2021
Laura Ochoa-Callejero und 23 weitere autoren -
“Suffocating” tumors by blocking adaptation to hypoxia – 07/09/2021
Bassam Janji und 1 weiterer autor -
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy – 01/01/2021
Bassam Janji und 11 weitere autoren -
Mitochondrial One-Carbon Flux has a Growth-Independent Role in Promoting Breast Cancer Metastasis – 27/05/2021
Johannes Meiser und 16 weitere autoren -
Epithelial to mesenchymal transition regulates surface pd-l1 via cmtm6 and cmtm7 induction in breast cancer – 09/03/2021
Malina Xiao und 10 weitere autoren -
Cxcl10 is an agonist of the cc family chemokine scavenger receptor ackr2/d6 – 02/03/2021
Martyna Szpakowska und 11 weitere autoren -
Targeting Cytoprotective Autophagy to Enhance Anticancer Therapies – 25/02/2021
Bassam Janji und 7 weitere autoren -
CXCR4-Binding Positron Emission Tomography Tracers Link Monocyte Recruitment and Endothelial Injury in Murine Atherosclerosis – 01/01/2021
Gwendalyn J. Randolph und 11 weitere autoren -
Selection of tumor-resistant variants following sustained natural killer cell-mediated immune stress – 01/02/2021
Salem Chouaib und 8 weitere autoren -
Specific ACKR2 modulators for use in therapy – 21/01/2021
Bassam Janji und 5 weitere autoren -
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) – 01/01/2021
Daniel J. Klionsky und 2928 weitere autoren -
Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34 – 01/11/2020
Bassam Janji und 5 weitere autoren -
Impact du ciblage du domaine de liaison de HIF-1α avec HIF-1b sur le paysage immunitaire du mélanome – 09/10/2020
Audrey Lequeux -
CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems – 05/10/2020
Bernhard Moser und 11 weitere autoren -
The ‘Holy Grail’ in Immuno-Oncology – 01/10/2020
Andreas Schläpfer und 4 weitere autoren -
Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway – 02/08/2020
Elisabeth Letellier und 19 weitere autoren -
Checkpoint Inhibitors and Engineered Cells – 29/06/2020
Massimo Giuliani und 1 weiterer autor -
The emerging impact of autophagy on the antitumor immune response – 15/05/2020
Meriem Hasmim und 6 weitere autoren -
Structural Features of an Extended C-Terminal Tail Modulate the Function of the Chemokine CCL21 – 07/04/2020
Natasha A. Moussouras und 7 weitere autoren -
Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy – 01/04/2020
Bassam Janji und 12 weitere autoren -
Assessing autophagy in archived tissue or how to capture autophagic flux from a tissue snapshot – 01/03/2020
Magali Humbert und 17 weitere autoren -
Firing up the cold tumors by targeting Vps34 – 01/01/2020
Bassam Janji und 4 weitere autoren -
The diverse and complex roles of atypical chemokine receptors in cancer – 01/01/2020
Elin Sjöberg und 5 weitere autoren -
Improving cancer immunotherapy by targeting the hypoxic tumor microenvironment – 01/09/2019
Muhammad zaeem NOMAN und 7 weitere autoren -
Impact of hypoxic tumor microenvironment and tumor cell plasticity on the expression of immune checkpoints – 28/08/2019
Bassam Janji und 10 weitere autoren -
The distinct roles of CXCR3 variants and their ligands in the tumor microenvironment – 18/06/2019
Andy Chevigne und 10 weitere autoren -
Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide – 01/04/2019
Lars Prestegarden und 19 weitere autoren -
Actin cytoskeleton remodeling drives breast cancer cell escape from natural killer-mediated cytotoxicity – 01/10/2018
Clément Thomas und 13 weitere autoren -
Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer – 28/08/2018
Victoria El Khoury und 13 weitere autoren -
Driving Natural Killer cells toward the melanoma tumor battlefield – 03/08/2018
Bassam Janji und 4 weitere autoren -
High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia – 03/08/2018
Marina Wierz und 4 weitere autoren -
Impact of targeting the autophagy related gene Beclin 1 on the immune landscape of melanoma – 09/07/2018
Tsolère Arakelian -
Inhibition of HIF1α-dependent upregulation of phospho-L-Plastin resensitizes multiple myeloma cells to frontline therapy – 01/06/2018
Bassam Janji und 10 weitere autoren -
Targeting autophagy in the tumor microenvironment – 25/04/2018
Bassam Janji und 2 weitere autoren -
Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia – 05/04/2018
Marina Wierz und 12 weitere autoren -
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT – 03/04/2018
Bassam Janji und 10 weitere autoren -
Targeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield – 03/04/2018
Bassam Janji und 2 weitere autoren -
Driving cytotoxic natural killer cells into melanoma – 01/01/2018
Bassam Janji und 8 weitere autoren -
Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner – 31/10/2017
Bassam Janji und 15 weitere autoren -
Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A – 05/09/2017
Simone Niclou und 10 weitere autoren -
The role of autophagy in anti-tumour immune response mediated by Natural Killer cells – 26/06/2017
Takouhie Mgrditchian -
Human CD56dimCD16dimCells As an Individualized Natural Killer Cell Subset – 19/06/2017
Jacques Zimmer und 11 weitere autoren -
Cutting edge – 15/02/2017
Salem Chouaib und 9 weitere autoren -
Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure – 01/02/2017
Salem Chouaib und 8 weitere autoren -
The critical role of hypoxia in tumor-mediated immunosuppression – 01/02/2017
Bassam Janji und 5 weitere autoren -
The immune checkpoint ligand PD-l1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200 – 02/01/2017
Salem Chouaib und 8 weitere autoren -
Activation of NK cells and disruption of PD-L1/PD-1 axis – 01/01/2017
Massimo Giuliani und 2 weitere autoren -
Mesenchymal stromal cells can regulate the immune response in the tumor microenvironment – 01/12/2016
Alessandro Poggi und 1 weiterer autor -
Hijacker of the antitumor immune response – 18/11/2016
Bassam Janji und 8 weitere autoren -
Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel–Lindau Gene Mutation Status – 01/10/2016
Salem Chouaib und 18 weitere autoren -
miR-210 and hypoxic microvesicles – 01/09/2016
Salem Chouaib und 3 weitere autoren -
Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer – 02/04/2016
Salem Chouaib und 10 weitere autoren -
CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis – 22/03/2016
Clément Thomas und 8 weitere autoren -
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) – 21/01/2016
Daniel J. Klionsky und 2461 weitere autoren -
Autophagy Activation in the Tumor Microenvironment – 01/01/2016
Bassam Janji und 5 weitere autoren -
Erratum to – 01/01/2016
Daniel J. Klionsky und 2461 weitere autoren -
Cell-free DNA and next-generation sequencing in the service of personalized medicine for lung cancer – 01/01/2016
Victoria El Khoury und 3 weitere autoren -
Role of Autophagy in Tumor Progression and Regression – 01/01/2016
Bassam Janji und 1 weiterer autor -
The multifaceted role of autophagy in tumor evasion from immune surveillance – 01/01/2016
Bassam Janji und 12 weitere autoren -
Autophagy regulation of the tumor immunity: An old housekeeper for a new function – 16/12/2015
Tsolère Arakelian und 6 weitere autoren -
miR-181a modulates acute myeloid leukemia susceptibility to natural killer cells – 02/12/2015
Salem Chouaib und 10 weitere autoren -
The selective degradation of synaptic connexin 43 protein by hypoxia-induced autophagy impairs natural killer cell-mediated tumor cell killing – 25/09/2015
Salem Chouaib und 4 weitere autoren -
Tumor-promoting effects of myeloid-derived suppressor cells are potentiated by hypoxia-induced expression of miR-210 – 15/09/2015
Salem Chouaib und 6 weitere autoren -
Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts – 27/08/2015
Jérôme Paggetti und 11 weitere autoren -
Epigenetic activity of peroxisome proliferator-activated receptor gamma agonists increases the anticancer effect of histone deacetylase inhibitors on multiple myeloma cells – 19/06/2015
Nassera Aouali und 8 weitere autoren -
Targeting WNT1-inducible signaling pathway protein 2 alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression – 23/04/2015
Salem Chouaib und 10 weitere autoren -
Hypoxia – 01/01/2015
Salem Chouaib und 6 weitere autoren -
ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy – 01/12/2014
Salem Chouaib und 21 weitere autoren -
Hypoxia: A key feature of the tumor microenvironment triggers several mechanisms of evasion from natural killer and cytotoxic T lymphocytes surveillance – 20/11/2014
Bassam Janji und 9 weitere autoren -
Autophagy – 01/11/2014
Bassam Janji und 6 weitere autoren -
Hypoxia-induced autophagy in tumor cells: a key target for improving cancer immunotherapy – 14/09/2014
Jérôme Paggetti und 4 weitere autoren -
Bronchial airway gene expression in smokers with lung or head and neck cancer – 01/04/2014
Eric Van Dyck und 15 weitere autoren -
EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction – 01/07/2013
Salem Chouaib und 6 weitere autoren -
Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from t-cell-mediated lysis – 15/04/2013
Salem Chouaib und 16 weitere autoren -
Guidelines for the use and interpretation of assays for monitoring autophagy – 01/04/2012
Daniel J. Klionsky und 1268 weitere autoren -
Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression – 15/09/2011
Salem Chouaib und 10 weitere autoren -
MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia – 19/04/2011
Etienne Moussay und 10 weitere autoren -
Microenvironmental hypoxia orchestrating the cell stroma cross talk, tumor progression and antitumor response – 01/01/2011
Salem Chouaib und 7 weitere autoren -
Quantitative pre-clinical imaging of hypoxia and vascularity using MRI and PET – 01/01/2024
Georgia Kanli und 9 weitere autoren -
Simultaneous Image Quality Improvement and Artefacts Correction in Accelerated MRI – 23/10/2024
Georgia Kanli und 4 weitere autoren -
Multi-parametric MRI to FMISO PET Synthesis for Hypoxia Prediction in Brain Tumors – 09/10/2024
Daniele Perlo und 8 weitere autoren -
Addressing Artefacts in Anatomical MR Images – 01/05/2024
Selma Boudissa und 4 weitere autoren -
Early-life influenza A (H1N1) infection independently programs brain connectivity, HPA AXIS and tissue-specific gene expression profiles – 11/03/2024
Jonathan Turner und 10 weitere autoren -
Corrigendum to ‘Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging–Guided Focused Ultrasound–Induced Blood–Brain Barrier Opening in a Mouse Glioblastoma Model’ [Ultrasound in Med & Biol. 49 (2023) 1082-1090, (S0301562922006664), (10.1016/j.ultrasmedbio.2022.12.006)] – 01/01/2024
Yanrong Zhang und 13 weitere autoren -
Predicting Hypoxia in Brain Tumors from Multiparametric MRI – 25/01/2024
Olivier Keunen und 3 weitere autoren -
Immune cell identity behind the Ktrans mapping of mouse glioblastoma – 21/06/2023
Max Wintermark und 13 weitere autoren -
Large-Scale Deep Learning Medical Image Methodology and Applications using Multiple GPUs – 12/10/2023
Ezhilmathi Krishnasamy und 5 weitere autoren -
Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging–Guided Focused Ultrasound–Induced Blood–Brain Barrier Opening in a Mouse Glioblastoma Model – 01/01/2023
Max Wintermark und 13 weitere autoren -
Author Correction – 26/01/2023
Spyridon Bakas und 278 weitere autoren -
Federated learning enables big data for rare cancer boundary detection – 05/12/2022
Spyridon Bakas und 278 weitere autoren -
Deciphering Human Glioblastoma Invasion Using a Developmental Mature Rat Brain Organoid Model – 15/11/2022
Wenjing Zhou und 30 weitere autoren -
The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model – 06/09/2022
Bassam Janji und 7 weitere autoren -
Federated Learning Enables Big Data for Rare Cancer Boundary Detection – 22/04/2022
Spyridon Bakas und 278 weitere autoren -
Molecular Identity Changes of Tumor-Associated Macrophages and Microglia after MRgFUS induced BBB Opening in a Mouse Glioblastoma Model – 15/03/2022
Max Wintermark und 13 weitere autoren -
Exploiting Liver CT scans in Colorectal Carcinoma genomics mutation classification – 01/01/2022
Daniele Perlo und 6 weitere autoren -
Relationship between Metabolically Unhealthy Obesity and Visceral Adipose Tissue in Youth – 01/12/2021
Hanène Samouda und 5 weitere autoren -
Current landscape and future perspectives in preclinical MR and PET imaging of brain metastasis – 14/10/2021
Frits Thorsen und 5 weitere autoren -
Inhibition of GBM invasion by the A-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid (AMPA) Glutamate receptor antagonist Perampanel – 09/09/2021
Katharina Sarnow und 3 weitere autoren -
Non-invasive, neurotoxic surgery reduces seizures in a rat model of temporal lobe epilepsy – 01/09/2021
Max Wintermark und 13 weitere autoren -
Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors – 18/06/2021
Anaïs Oudin und 16 weitere autoren -
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology – 01/12/2020
Simone Niclou und 40 weitere autoren -
Spatially regularized estimation of the tissue homogeneity model parameters in DCE-MRI using proximal minimization – 01/12/2019
Michal Bartos und 5 weitere autoren -
Improved drug delivery to brain metastases by peptide-mediated permeabilization of the blood–brain barrier – 01/11/2019
Frits Thorsen und 17 weitere autoren -
THER-11. Peptide mediated permeabilization of the blood-brain-barrier improves drug delivery to brain metastasis – 01/08/2019
Synnøve Nymark Aasen und 17 weitere autoren -
Iterative methods for fast reconstruction of undersampled dynamic contrast-enhanced MRI data – 01/01/2019
Hynek Walner und 6 weitere autoren -
The small inhibitor WM-1119 effectively targets KAT6A-rearranged AML, but not KMT2A-rearranged AML, despite shared KAT6 genetic dependency – 08/10/2024
Georges Lacaud und 15 weitere autoren -
Protocol for isolating leukemia-derived extracellular vesicles from the spleen of preclinical models of leukemia using ultracentrifugation – 05/08/2024
Etienne Moussay und 5 weitere autoren -
Assessment of translation rate in leukemic cells and immune cells of the microenvironment by OPP protein synthesis assay – 02/07/2024
Anne Largeot und 4 weitere autoren -
Protein arginine methyltransferase 2 controls inflammatory signaling in acute myeloid leukemia – 20/06/2024
Laurent Delva und 16 weitere autoren -
Eμ-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia – 18/04/2024
Jérôme Paggetti und 4 weitere autoren -
Characterization of the tumor and its microenvironment in chronic lymphocytic leukemia – 14/05/2024
Iria Fernandez Botana -
Editorial – 08/05/2024
Martin Böttcher und 2 weitere autoren -
PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle – 28/02/2024
Johannes Meiser und 20 weitere autoren -
Minimal information for studies of extracellular vesicles (MISEV2023) – 01/02/2024
Joshua A. Welsh und 49 weitere autoren -
Flow cytometry-assisted quantification of cell cycle arrest in cancer cells treated with CDK4/6 inhibitors – 22/08/2023
Giulia Petroni und 4 weitere autoren -
Power out chronic lymphocytic leukemia – 03/08/2023
Jérôme Paggetti und 1 weiterer autor -
Molecular determinants of immunogenic cell death elicited by radiation therapy – 01/01/2023
Lorenzo Galluzzi und 3 weitere autoren -
Role of AHR and HIF1α transcription factors in normal and chronic lymphocytic leukemia B lymphocytes – 21/12/2023
Susanne Gonder -
Targeting mRNA translation aberrations – 01/01/2023
Etienne Moussay und 3 weitere autoren -
Interleukin-27 tackles immunosuppression in chronic lymphocytic leukemia – 03/11/2023
Jérôme Paggetti und 3 weitere autoren -
Interleukin-27 potentiates CD8+ T-cell-mediated anti-tumor immunity in chronic lymphocytic leukemia – 22/06/2023
Jérôme Paggetti und 16 weitere autoren -
Immunologically relevant effects of radiation therapy on the tumor microenvironment – 18/05/2023
Lorenzo Galluzzi und 4 weitere autoren -
Formate promotes invasion and metastasis in reliance on lipid metabolism – 30/08/2023
Johannes Meiser und 26 weitere autoren -
Type I interferon and cancer – 01/01/2023
Jitka Fucikova und 6 weitere autoren -
High-dimensional single-cell definition of CLL T cells identifies Galectin-9 as novel immunotherapy target – 30/08/2023
Martina Seiffert und 28 weitere autoren -
Inhibition of MYC translation through targeting of the newly identified PHB-EIF4F complex as therapeutic strategy inchronic lymphocytic leukemia (CLL) – 01/08/2023
Anne Largeot und 32 weitere autoren -
The DNA Damage Response and Inflammation in Cancer – 07/04/2023
Lorenzo Galluzzi und 5 weitere autoren -
Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as a therapeutic strategy in CLL – 01/01/2023
Anne Largeot und 32 weitere autoren -
SOHO State of the Art Updates and Next Questions | Infections in Chronic Lymphocytic Leukemia Patients – 10/02/2023
Carsten U Niemann und 2 weitere autoren -
Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells – 01/01/2023
Johannes Meiser und 33 weitere autoren -
The protective role of the microenvironment in hairy cell leukemia treatment – 08/03/2023
Pablo Elias Morande und 5 weitere autoren -
PKM2 diverts glycolytic flux in dependence on formate overflow – 23/01/2023
Johannes Meiser und 17 weitere autoren -
Role of AHR, HIF-1α and IL-27 In T-cell-mediated immunity in chronic lymphocytic leukemia – 09/01/2023
Giulia Pagano -
Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses – 15/09/2022
Jérôme Paggetti und 16 weitere autoren -
T cell landscape definition by multi-omics identifies Galectin-9 as novel immunotherapy target in chronic lymphocytic leukemia – 16/12/2022
Martina Seiffert und 26 weitere autoren -
Single-Cell Omics Analyses Identify the TIM-3 Ligand Galectin-9 As Novel Immunotherapy Target for Chronic Lymphocytic Leukemia – 15/11/2022
Laura Llaó Cid und 15 weitere autoren -
Small extracellular vesicles – 27/09/2022
Ernesto Gargiulo und 3 weitere autoren -
The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model – 06/09/2022
Bassam Janji und 7 weitere autoren -
Natural killer cells and bone marrow mesenchymal stem cells – 28/07/2022
Jérôme Paggetti und 2 weitere autoren -
Targeting translation by disrupting the newly identified prohibitin-eif4f complex as a novel therapeutic strategy in chronic lymphocytic leukemia – 01/06/2022
Anne Largeot und 9 weitere autoren -
Editor’s Note – 15/04/2022
Yosra Messai und 21 weitere autoren -
PRMT2 : un facteur épigénétique anti-inflammatoire impliqué dans l’agressivité des leucémies aiguës myéloblastiques – 01/03/2022
C. Sauter und 14 weitere autoren -
A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia – 28/02/2022
Agnieszka Goral und 17 weitere autoren -
Editorial – 03/02/2022
Martina Seiffert und 2 weitere autoren -
Editorial – 17/01/2022
Etienne Moussay und 2 weitere autoren -
Editorial – 15/12/2021
Jérôme Paggetti und 2 weitere autoren -
Impact of small extracellular vesicles on anti-tumor immunity in chronic lymphocytic leukemia in vivo – 17/11/2021
Ernesto Gargiulo -
The tumor microenvironment-dependent transcription factors ahr and hif-1α are dispensable for leukemogenesis in the eµ-tcl1 mouse model of chronic lymphocytic leukemia – 08/09/2021
Susanne Gonder und 7 weitere autoren -
In Vitro Sensitivity to Venetoclax and Microenvironment Protection in Hairy Cell Leukemia – 26/07/2021
Pablo Elias Morande und 14 weitere autoren -
AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms – 22/07/2021
Pablo Oppezzo und 19 weitere autoren -
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy – 01/01/2021
Bassam Janji und 11 weitere autoren -
Immunomodulatory effects of different intravenous immunoglobulin preparations in chronic lymphocytic leukemia – 21/06/2021
Mercedes Borge und 8 weitere autoren -
Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling – 24/05/2021
Clément Thomas und 11 weitere autoren -
Method for the Analysis of the Tumor Microenvironment by Mass Cytometry – 20/10/2020
Susanne Gonder und 8 weitere autoren -
Diagnostic and Therapeutic Potential of Extracellular Vesicles in B-Cell Malignancies – 29/09/2020
Ernesto Gargiulo und 4 weitere autoren -
Characterisation of the tumour microenvironment in chronic lymphocytic leukemia by mass cytometry: implications for immunotherapy – 14/09/2020
Marina Wierz -
Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway – 02/08/2020
Elisabeth Letellier und 19 weitere autoren -
Actin remodeling and vesicular trafficking at the tumor cell side of the immunological synapse direct evasion from cytotoxic lymphocytes – 01/01/2020
Andrea Michela Biolato und 6 weitere autoren -
Eomes and IL-10 Regulate Anti-Tumor Activity of T Cells in Chronic Lymphocytic Leukemia – 13/11/2019
Laura Llao Cid und 10 weitere autoren -
Impact of hypoxic tumor microenvironment and tumor cell plasticity on the expression of immune checkpoints – 28/08/2019
Bassam Janji und 10 weitere autoren -
Hematological malignancy-derived small extracellular vesicles and tumor microenvironment – 27/05/2019
Ernesto Gargiulo und 2 weitere autoren -
The B-side of cancer immunity – 13/05/2019
Anne Largeot und 4 weitere autoren -
HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells – 11/04/2019
Carmen Garrido und 18 weitere autoren -
Chronic Lymphocytic Leukaemia-derived exosomes: A potential strategy for immune escape – 01/01/2019
Ernesto Gargiulo -
Chronic Lymphocytic Leukaemia-derived small extracellular vesicles: A potential strategy for immune escape – 01/01/2019
Ernesto Gargiulo -
Purification of leukemia-derived exosomes to study microenvironment modulation – 01/01/2019
Jérôme Paggetti und 5 weitere autoren -
Transgenic expression of the RNA binding protein IMP2 stabilizes miRNA targets in murine microsteatosis – 01/10/2018
Azim Dehghani Amirabad und 6 weitere autoren -
Driving Natural Killer cells toward the melanoma tumor battlefield – 03/08/2018
Bassam Janji und 4 weitere autoren -
High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia – 03/08/2018
Marina Wierz und 4 weitere autoren -
Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia – 05/04/2018
Marina Wierz und 12 weitere autoren -
The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model – 23/03/2018
Marina Wierz und 7 weitere autoren -
Exosome proteins and RNAas biomarkers of hematologic malignancies development and progression – 01/01/2018
Ernesto Gargiulo -
Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner – 31/10/2017
Bassam Janji und 15 weitere autoren -
Tumor-derived exosomes modulate PD-L1 expression in monocytes – 01/01/2017
Martina Seiffert und 20 weitere autoren -
Hijacker of the antitumor immune response – 18/11/2016
Bassam Janji und 8 weitere autoren -
A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B-cells – 01/07/2016
Sandrine Medves und 15 weitere autoren -
Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer – 02/04/2016
Salem Chouaib und 10 weitere autoren -
BCR engagement in CLL – 28/01/2016
Jérôme Paggetti und 1 weiterer autor -
Assessing cellular and circulating miRNA recovery – 20/01/2016
Victoria El Khoury und 4 weitere autoren -
Autophagy Activation in the Tumor Microenvironment – 01/01/2016
Bassam Janji und 5 weitere autoren -
The multifaceted role of autophagy in tumor evasion from immune surveillance – 01/01/2016
Bassam Janji und 12 weitere autoren -
Autophagy regulation of the tumor immunity: An old housekeeper for a new function – 16/12/2015
Tsolère Arakelian und 6 weitere autoren -
Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts – 27/08/2015
Jérôme Paggetti und 11 weitere autoren -
ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy – 01/12/2014
Salem Chouaib und 21 weitere autoren -
Hypoxia: A key feature of the tumor microenvironment triggers several mechanisms of evasion from natural killer and cytotoxic T lymphocytes surveillance – 20/11/2014
Bassam Janji und 9 weitere autoren -
Hypoxia-induced autophagy in tumor cells: a key target for improving cancer immunotherapy – 14/09/2014
Jérôme Paggetti und 4 weitere autoren -
Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia – 01/08/2014
Victoria El Khoury und 7 weitere autoren -
Bronchial airway gene expression in smokers with lung or head and neck cancer – 01/04/2014
Eric Van Dyck und 15 weitere autoren -
Chronic Lymphocytic Leukemia-Derived Exosomes Stimulate Cells From The Microenvironment – 15/11/2013
Jérôme Paggetti und 2 weitere autoren -
A MiR-142-3p/EGR2 Feedback Circuitry In Human CSF-1 Driven Differentiation of Monocytes Into Macrophages – 18/11/2011
Brice Lagrange und 7 weitere autoren -
Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression – 15/09/2011
Salem Chouaib und 10 weitere autoren -
MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia – 19/04/2011
Etienne Moussay und 10 weitere autoren -
Peroxisome proliferator-activated receptor γ agonists potentiate the cytotoxic effect of valproic acid in multiple myeloma cells – 01/12/2009
Guy Berchem und 10 weitere autoren -
The Histone Acetyl-Transferase MOZ Cooperates with the Historic Methyl-Transferase MILL to Regulate HOX Gene Expression in Human Hematopoietic Stem Cells – 16/11/2008
Jérôme Paggetti und 7 weitere autoren -
Integrated single-cell analysis reveals distinct epigenetic-regulated cancer cell states and a heterogeneity-guided core signature in tamoxifen-resistant breast cancer – 18/11/2024
Victor X. Jin und 9 weitere autoren -
Adenoviral delivery of the CIITA transgene induces T-cell-mediated killing in glioblastoma organoids – 13/11/2024
Simone P. Niclou und 13 weitere autoren -
Patient-based multilevel transcriptome exploration highlights relevant chemokines and chemokine receptor axes in glioblastoma – 30/09/2024
Giulia D’Uonnolo und 10 weitere autoren -
Digital voice-based biomarker for monitoring respiratory quality of life – 01/10/2024
Vladimir Despotovic und 6 weitere autoren -
Metformin impacts the differentiation of mouse bone marrow cells into macrophages affecting tumour immunity – 30/09/2024
Alessandro Michelucci und 15 weitere autoren -
PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation – 16/07/2024
Alessandro Michelucci und 20 weitere autoren -
consICA – 13/07/2024
Petr Nazarov und 4 weitere autoren -
AllergoOncology – 01/01/2024
Aurélie Poli und 29 weitere autoren -
Most accurate mutations in SARS-CoV-2 genomes identified in Uzbek patients show novel amino acid changes – 31/05/2024
Ibrokhim Y. Abdurakhmonov und 10 weitere autoren -
Enhancing the opportunities for cholangiocarcinoma precision therapy – 16/01/2024
Javier Vaquero und 2 weitere autoren -
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts – 02/04/2024
Anna Golebiewska und 24 weitere autoren -
Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells – 25/03/2024
Madhuri S. Salker und 13 weitere autoren -
Glioma subtype classification from histopathological images using in-domain and out-of-domain transfer learning – 15/03/2024
Vladimir Despotovic und 8 weitere autoren -
Early-life influenza A (H1N1) infection independently programs brain connectivity, HPA AXIS and tissue-specific gene expression profiles – 11/03/2024
Jonathan Turner und 10 weitere autoren -
PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation – 09/02/2024
Alessandro Michelucci und 17 weitere autoren -
Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts – 12/12/2023
Anna Golebiewska und 21 weitere autoren -
Inhibition of MIR-146A-5P decreases progression of melanoma brain metastasis via notch pathway dysregulation in astrocytes – 10/11/2023
E. K. Rigg und 19 weitere autoren -
Targeting the dna damage response in glioblastoma propagating cells: from molecular mechanisms to precision medicine – 10/11/2023
Alexandros Pailas und 9 weitere autoren -
Inhibition of extracellular vesicle-derived miR-146a-5p decreases progression of melanoma brain metastasis via Notch pathway dysregulation in astrocytes – 01/10/2023
Emma Rigg und 19 weitere autoren -
Glioma subtype classification from histopathological images using in-domain and out-of-domain transfer learning: An experimental study – 29/09/2023
Vladimir Despotovic und 8 weitere autoren -
Integrative omics analysis of IDH1 mutant glioma patients reveals alterations in butyrate metabolism – 08/09/2023
Sabrina Fritah und 9 weitere autoren -
Stability of stochastic dynamic systems of a random structure with Markov switching in the presence of concentration points – 16/08/2023
Petr Nazarov und 3 weitere autoren -
Inhibition of MYC translation through targeting of the newly identified PHB-EIF4F complex as therapeutic strategy inchronic lymphocytic leukemia (CLL) – 01/08/2023
Anne Largeot und 32 weitere autoren -
Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response – 27/06/2023
Stephanie Kreis und 11 weitere autoren -
Identification of Delta Variant-Specific Mutations of SARS-CoV-2 Genomes Found in Uzbek Patients by Amplicon Sequencing – 01/07/2023
Ibrokhim Abdurakhmonov und 9 weitere autoren -
Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as a therapeutic strategy in CLL – 01/01/2023
Anne Largeot und 32 weitere autoren -
Impact of IDH Mutations, the 1p/19q Co-Deletion and the G-CIMP Status on Alternative Splicing in Diffuse Gliomas – 06/06/2023
Eric Van Dyck und 4 weitere autoren -
Stability of stochastic dynamic systems of a random structure with Markov switchings in the presence of concentration points – 19/05/2023
Taras Lukashiv und 3 weitere autoren -
Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking – 22/03/2023
Christoph Plass und 19 weitere autoren -
Allergic airway inflammation delays glioblastoma progression and reinvigorates systemic and local immunity in mice – 01/01/2022
Aurélie Poli und 16 weitere autoren -
Stabilization of Stochastic Dynamical Systems of a Random Structure with Markov Switches and Poisson Perturbations – 01/02/2023
Petr Nazarov und 4 weitere autoren -
Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses – 15/09/2022
Jérôme Paggetti und 16 weitere autoren -
Stabilization of stochastic dynamical systems of a random structure with Markov switches and Poisson perturbations – 15/12/2022
Taras Lukashiv und 4 weitere autoren -
Vocal biomarker predicts fatigue in people with COVID-19 – 22/11/2022
Guy Fagherazzi und 7 weitere autoren -
Deciphering Human Glioblastoma Invasion Using a Developmental Mature Rat Brain Organoid Model – 15/11/2022
Wenjing Zhou und 30 weitere autoren -
Discovery and Analytical Validation of a Vocal Biomarker to Monitor Anosmia and Ageusia in Patients with COVID-19 – 07/09/2022
Guy Fagherazzi und 6 weitere autoren -
A voice-based biomarker for monitoring symptom resolution in adults with COVID-19 – 20/10/2022
Guy Fagherazzi und 8 weitere autoren -
Extracellular vesicle derived-MIR-146A increases melanoma brain metastasis progression via notch signalling pathway dysregulation – 05/09/2022
E. K. Rigg und 16 weitere autoren -
Glioblastoma-instructed microglia transit to heterogeneous phenotypic states with dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts – 05/09/2022
Yahaya Abubakar Yabo und 8 weitere autoren -
Ten quick tips for biomarker discovery and validation analyses using machine learning – 11/08/2022
Enrico Glaab und 7 weitere autoren -
Long COVID Symptomatology After 12 Months and Its Impact on Quality of Life According to Initial Coronavirus Disease 2019 Disease Severity – 05/08/2022
Guy Fagherazzi und 8 weitere autoren -
Linear system identifiability from single-cell data – 01/07/2022
Jorge Goncalves und 2 weitere autoren -
Model-based assessment of COVID-19 epidemic dynamics by wastewater analysis – 25/06/2022
Atte Aalto und 7 weitere autoren -
BIODICA – 06/04/2022
Nicolas Captier und 8 weitere autoren -
Oncolytic H-1 Parvovirus Hijacks Galectin-1 to Enter Cancer Cells – 11/05/2022
Antonio Marchini und 8 weitere autoren -
ORFhunteR – 01/05/2022
Vasily V. Grinev und 4 weitere autoren -
Designing of learning content for a university online course – 01/04/2022
V. M. Lutkovski und 1 weiterer autor -
A DNA Damage Repair Signature in Pediatric High-Grade Gliomas: XRCC1 and PARP1, Key Biomarkers – 01/11/2021
N. Entz-Werle und 6 weitere autoren -
In silico approach for validating and unveiling new applications for prognostic biomarkers of endometrial cancer – 09/10/2021
Eva Coll de la Rubia und 7 weitere autoren -
DECONbench – 02/10/2021
Clémentine Decamps und 50 weitere autoren -
XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase – 27/09/2021
Eric Van Dyck und 16 weitere autoren -
Allergic airway inflammation impacts tumor take and delays experimental glioblastoma progression – 01/09/2021
Aurélie Poli und 13 weitere autoren -
Phenotypic heterogeneity and plasticity as resistance mechanisms in glioblastoma – 01/09/2021
Yahaya Abubakar Yabo und 5 weitere autoren -
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα – 25/06/2021
Achim Leutz und 10 weitere autoren -
A DNA repair and cell cycle gene expression signature in pediatric high‐grade gliomas – 07/05/2021
Natacha Entz‐werlé und 13 weitere autoren -
Integrative approaches for analysis of mRNA and microRNA high-throughput data – 01/01/2021
Petr Nazarov und 1 weiterer autor -
AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion – 01/12/2020
Simone Niclou und 18 weitere autoren -
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology – 01/12/2020
Simone Niclou und 40 weitere autoren -
Systematic Transcriptional Profiling of Responses to STAT1- and STAT3-Activating Cytokines in Different Cancer Types – 06/11/2020
Stephanie Kreis und 9 weitere autoren -
Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz – 01/10/2020
Pavlo Lutsik und 10 weitere autoren -
Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics – 26/08/2020
Mi Yang und 50 weitere autoren -
Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway – 02/08/2020
Elisabeth Letellier und 19 weitere autoren -
Deconvolution of “big data” in cancer genomics: from pancancer level to single cells – 09/07/2020
M. Chepeleva und 5 weitere autoren -
Independent component analysis of cancer transcriptomes: optimization of parameters and improvement of interpretability – 09/07/2020
M. Chepeleva und 3 weitere autoren -
Identification of a blood-based protein biomarker panel for lung cancer detection – 01/06/2020
Victoria El Khoury und 22 weitere autoren -
Guidelines for cell-type heterogeneity quantification based on a comparative analysis of reference-free DNA methylation deconvolution software – 13/01/2020
Magali Richard und 44 weitere autoren -
Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment – 01/12/2019
Simone Niclou und 21 weitere autoren -
Genome-wide shRNA screen identifies candidate genes driving glioblastoma invasion – 01/11/2019
Anne Schuster und 9 weitere autoren -
Intrinsic tumor plasticity in glioblastoma allows for recreation of stem like-states and efficient tumor cell adaveveion to new microenvironments – 01/11/2019
Anna Golebiewska und 12 weitere autoren -
Connecting histopathology imaging and proteomics in kidney cancer through machine learning – 01/10/2019
Francisco Azuaje und 3 weitere autoren -
Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients – 18/09/2019
Petr Nazarov und 8 weitere autoren -
Power-law behavior of the alternative splicing of exons in human transcriptome – 02/09/2019
Vasily V. Grinev und 2 weitere autoren -
Independent component analysis for unraveling the complexity of cancer omics datasets – 01/09/2019
Andrei Zinovyev und 11 weitere autoren -
Genome-wide shRNA screen identifies candidate genes driving glioblastoma invasion – 03/08/2019
Anne Schuster und 9 weitere autoren -
A 3D brain organoid coculture system delineates the invasive cell components in glioblastoma – 01/08/2019
Wenjing Zhou und 11 weitere autoren -
Intrinsic tumor plasticity in glioblastoma allows for recreation of stem like-states and efficient tumor cell adaptation to new microenvironments – 01/08/2019
Anna Golebiewska und 12 weitere autoren -
Tumor suppressor miR-215 counteracts hypoxia-induced colon cancer stem cell activity – 28/05/2019
Elisabeth Letellier und 11 weitere autoren -
Hub genes in a pan-cancer co-expression network show potential for predicting drug responses – 05/03/2019
Francisco Azuaje und 8 weitere autoren -
RNAi/CRISPR Screens – 01/01/2019
Anne Schuster und 6 weitere autoren -
A DNA repair and cell-cycle gene expression signature in primary and recurrent glioblastoma – 01/01/2019
Eric Van Dyck und 11 weitere autoren -
Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer – 28/08/2018
Victoria El Khoury und 13 weitere autoren -
Predicting clinical outcome of neuroblastoma patients using an integrative network-based approach – 07/06/2018
Francisco Azuaje und 7 weitere autoren -
Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways – 01/12/2017
Simone Niclou und 16 weitere autoren -
Analysis of the dynamic co-expression network of heart regeneration in the zebrafish – 31/05/2016
Francisco Azuaje und 17 weitere autoren -
What do we learn from spheroid culture systems? Insights from tumorspheres derived from primary colon cancer tissue – 08/01/2016
Komal Qureshi-Baig und 6 weitere autoren -
Whole transcriptome microarrays identify long non-coding RNAs associated with cardiac hypertrophy – 01/09/2015
Yvan Devaux und 9 weitere autoren -
Verification of the biomarker candidates for non-small-cell lung cancer using a targeted proteomics approach – 06/03/2015
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Transcriptional response to cardiac injury in the zebrafish – 03/10/2014
Francisco Azuaje und 9 weitere autoren -
Technical considerations for large-scale parallel reaction monitoring analysis – 04/04/2014
Bruno Domon und 3 weitere autoren -
Correction – 18/04/2013
Zsuzsa Rakosy und 10 weitere autoren -
Use of circulating microRNAs to diagnose acute myocardial infarction – 01/03/2012
Daniel Wagner und 10 weitere autoren -
MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia – 19/04/2011
Etienne Moussay und 10 weitere autoren -
Quantitative pre-clinical imaging of hypoxia and vascularity using MRI and PET – 01/01/2024
Georgia Kanli und 9 weitere autoren -
Simultaneous Image Quality Improvement and Artefacts Correction in Accelerated MRI – 23/10/2024
Georgia Kanli und 4 weitere autoren -
Multi-parametric MRI to FMISO PET Synthesis for Hypoxia Prediction in Brain Tumors – 09/10/2024
Daniele Perlo und 8 weitere autoren -
Addressing Artefacts in Anatomical MR Images – 01/05/2024
Selma Boudissa und 4 weitere autoren -
Early-life influenza A (H1N1) infection independently programs brain connectivity, HPA AXIS and tissue-specific gene expression profiles – 11/03/2024
Jonathan Turner und 10 weitere autoren -
Corrigendum to ‘Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging–Guided Focused Ultrasound–Induced Blood–Brain Barrier Opening in a Mouse Glioblastoma Model’ [Ultrasound in Med & Biol. 49 (2023) 1082-1090, (S0301562922006664), (10.1016/j.ultrasmedbio.2022.12.006)] – 01/01/2024
Yanrong Zhang und 13 weitere autoren -
Predicting Hypoxia in Brain Tumors from Multiparametric MRI – 25/01/2024
Olivier Keunen und 3 weitere autoren -
Immune cell identity behind the Ktrans mapping of mouse glioblastoma – 21/06/2023
Max Wintermark und 13 weitere autoren -
Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging–Guided Focused Ultrasound–Induced Blood–Brain Barrier Opening in a Mouse Glioblastoma Model – 01/01/2023
Max Wintermark und 13 weitere autoren -
Author Correction – 26/01/2023
Spyridon Bakas und 278 weitere autoren -
Federated learning enables big data for rare cancer boundary detection – 05/12/2022
Spyridon Bakas und 278 weitere autoren -
Deciphering Human Glioblastoma Invasion Using a Developmental Mature Rat Brain Organoid Model – 15/11/2022
Wenjing Zhou und 30 weitere autoren -
The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model – 06/09/2022
Bassam Janji und 7 weitere autoren -
Federated Learning Enables Big Data for Rare Cancer Boundary Detection – 22/04/2022
Spyridon Bakas und 278 weitere autoren -
Molecular Identity Changes of Tumor-Associated Macrophages and Microglia after MRgFUS induced BBB Opening in a Mouse Glioblastoma Model – 15/03/2022
Max Wintermark und 13 weitere autoren -
Relationship between Metabolically Unhealthy Obesity and Visceral Adipose Tissue in Youth – 01/12/2021
Hanène Samouda und 5 weitere autoren -
Inhibition of GBM invasion by the A-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid (AMPA) Glutamate receptor antagonist Perampanel – 09/09/2021
Katharina Sarnow und 3 weitere autoren -
Non-invasive, neurotoxic surgery reduces seizures in a rat model of temporal lobe epilepsy – 01/09/2021
Max Wintermark und 13 weitere autoren -
Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors – 18/06/2021
Anaïs Oudin und 16 weitere autoren -
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology – 01/12/2020
Simone Niclou und 40 weitere autoren -
Is there a prominent role for MR spectroscopy in the clinical management of brain tumors? – 01/07/2020
Simone Niclou und 1 weiterer autor -
Spatially regularized estimation of the tissue homogeneity model parameters in DCE-MRI using proximal minimization – 01/12/2019
Michal Bartos und 5 weitere autoren -
Improved drug delivery to brain metastases by peptide-mediated permeabilization of the blood–brain barrier – 01/11/2019
Frits Thorsen und 17 weitere autoren -
THER-11. Peptide mediated permeabilization of the blood-brain-barrier improves drug delivery to brain metastasis – 01/08/2019
Synnøve Nymark Aasen und 17 weitere autoren -
Improved treatment of melanoma brain metastasis using a synthetic peptide – 01/11/2018
Synnove Nymark Aasen und 14 weitere autoren -
Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma – 01/10/2018
Olivier Keunen und 9 weitere autoren -
EGFL7 enhances surface expression of integrin α 5 β 1 to promote angiogenesis in malignant brain tumors – 01/09/2018
Mirko H.H. Schmidt und 17 weitere autoren -
The good drug, the bad barrier and the handy peptide: Improved treatment of experimental melanoma brain metastases using a synthetic peptide – 01/07/2018
Synnove Nymark Aasen und 10 weitere autoren -
Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways – 01/12/2017
Simone Niclou und 16 weitere autoren -
Subtraction of subcutaneous fat to improve the prediction of visceral adiposity – 01/08/2017
Hanène Samouda und 9 weitere autoren -
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation – 01/12/2016
Hrvoje Miletic und 29 weitere autoren -
Cardiometabolic risk – 01/06/2016
Hanène Samouda und 11 weitere autoren -
Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma – 31/05/2016
Simone Niclou und 18 weitere autoren -
Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma – 27/11/2015
Eyal Gottlieb und 19 weitere autoren -
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas – 17/01/2015
Rolf Bjerkvig und 18 weitere autoren
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Post-Doctoral Fellow in Brain Tumor Immunology (JA/PD1124/AP/NIG)
Department of Cancer Research – Neuro-Immunology Group